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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Hb S migrates with D in alkaline and alone in acid electrophoresis.
The gel electrophoresis pattern for hemoglobin S shows which of the following migration patterns?

A) Hb S migrates with D in alkaline and alone in acid electrophoresis.
B) Hb S migrates alone in alkaline and D in acid electrophoresis.
C) Hb S migrates with D in alkaline and A in acid electrophoresis.
D) Hb S migrates with A in alkaline and D in acid electrophoresis.

2. If Kappa or Lambda is predominant and CD5 is co-expressed with CD19 (CD19/CD5 dual positive lymphocyte population), and CD23 is expressed, chronic lymphocytic leukemia is a probable diagnosis. CD19 is normally found on normal B cell populations and CD5 is normally found on mature T cell populations.
However, CD5 is present on B cells in B-chronic lymphocytic leukemia or Mantle Cell Lymphoma, both abnormal B cell malignant processes.
CD23 expression is not consistent with Mantel cells as shown on the decision tree on the right.
A monoclonal B-cell population (Kappa or Lambda predominant) with expression of CD19, CD20, CD23, and co-expression of CD5 is consistent with which of the following?

A) A normal B cell
B) Chronic lymphocytic leukemia
C) A mature T cell
D) Mantle cell lymphoma

3. Chemistry
Estrogen and progesterone markers are most commonly used to provide prognostic information about:

A) Uterine cancer
B) Cervical cancer
C) Breast cancer
D) Menopause

4. Thyroid-stimulating immunoglobulins, or TSI's, are IgG antibodies that can bind to thyrotropin (TSH) receptors on the thyroid gland. TSIs mimic the action of TSH, causing excess secretion of thyroxine and triiodothyronine. The TSI level is abnormally high in persons with hyperthyroidism due to Graves' disease.
Which of the following is an autoantibody that binds to TSH receptor sites on thyroid cell membranes preventing thyroid-stimulating hormone binding?

A) Lupus erythematosus
B) Antithyroglobulin
C) Thyroid-stimulating immunoglobulins
D) Antimicrosomal antibodies
E) Thyroxin-binding globulins

5. A beam splitter is employed in a dual beam spectrophotometer.
Which of the following is not a component of a basic single beam spectrophotometer:

A) Beam splitter
B) Light source
C) Prism
D) Cuvette

Solutions: